All her attempts to finish the project were in vain.

Despite the man’s attempts to focus on his work, the woman’s incessant talking made his efforts to concentrate in vain.

As the woman passionately conveyed her message, the man’s distracted gaze suggested that her words might be in vain in the busy office environment.

The man’s attempts to focus on his work were in vain as the woman continued to talk in the bustling office.